Prolactin is a hormone that promotes milk production. Actually, Dr. Masterson says there are several. Secondly, there is no clear indication about the dosage for milk production versus GI symptoms. And finally, because metoclopramide passes through breast milk, there can be side effects for both mom and baby. Masterson reveals. As unpleasant as that is for baby, the side effects for mom are potentially much worse.
Masterson says that in addition to similar GI issues, headache, fatigue, dry mouth, and certain movement disorders , women may also find that metoclopramide triggers or worsens symptoms of anxiety and depression. At a time when moms are particularly vulnerable to the mood changes brought on by postpartum hormones and the stresses of feeding a newborn around the clock, a drug that carries a serious risk of depression may not be the best choice. Instead, she emphasizes the importance of getting support during the early days of breastfeeding.
Listing a study does not mean it has been evaluated by the U. Federal Government. Read our disclaimer for details. Last Update Posted : September 21, Study Description. Detailed Description:. Hypothesis: Early Use of oral metoclopramide can hasten and improve the establishment of lactogenesis II in mothers after preterm and term deliveries. Drug Information available for: Metoclopramide Metoclopramide hydrochloride. FDA Resources.
Arms and Interventions. Mothers will be given metoclopramide 10 mg 3 times a day for 7 days, 2 times a day from day 8 to 10 and once a day from 11th to 12th day. Mothers with pre-term deliveries will receive metoclopramide 10 mg 3 times a day, 2 times a day from 8th to 10th day and once a day from 11th to 12th day.
Mothers with full term deliveries will receive 10 mg metoclopramide, 3 times a day for the first 7 days, 2 times a day from 8th to 10th day, and once a day for day 11 to Mothers with full term deliveries will receive the placebo 10 mg three times a day, for 7 days, and two times a day from day 8 to day 10, and once a day from 11th to 12th day. Outcome Measures. Primary Outcome Measures : successful initiation of lactation as determined by lactogenesis II markers [ Time Frame: 7 days postpartum ].
Secondary Outcome Measures : weight change in baby 7 days after birth [ Time Frame: 14 days postpartum ] breastfeeding status at 14 days, 6 weeks, 3 months and 6 months after delivery [ Time Frame: 6 months postpartum ].
Eligibility Criteria. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Inclusion Criteria: All pregnant women who intend to breastfeed, from 28 weeks to term, who have not met the exclusion criteria Exclusion Criteria: Patients who have epilepsy or on anti-seizure medications, Patients who have a history of significant depression or are on antidepressant drugs Patients who have pheochromocytoma or uncontrolled hypertension Patients who have intestinal bleeding or obstruction Patients who have a known allergy or prior reaction to metoclopramide, or any other contraindications to the use of metoclopramide Patients who have diabetes and hyperprolactinaemia Patients with HIV infection Current pregnancy complicated by fetal congenital anomalies and multiple fetuses.
Contacts and Locations. Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. This is because those are issues helped by a higher level of prolactin hormone.
Concretely the following cases might be helped by Reglan metoclopramide :. Domperidone is another medication that has arguably more effect than Reglan when it comes to increasing milk supply.
It is however as of yet not approved by the U. FDA because of its side effects on the heart. As such it is not available to buy in the U. It is approved in other countries such as Canada.
Breast stimulation and the general supply and demand concept remains what most lactation specialists would recommend to increase milk supply. There are also several herbal supplements known to work very well for many women such as Milk Boost Tea. Nelson Metoclopramide to augment lactation, does it work?
Osouli, S. International Journal of Pediatrics, 5 10 , Domperidone versus metoclopramide: Self-reported side effects in a large sample of breastfeeding mothers who used these medications to increase milk production.
Clinical Lactation. Bazzano, A. Maternal experiences with and sources of information on galactagogues to support lactation: a cross-sectional study.
International journal of women's health, 9, — Article tags: Breastfeeding and maternity. Share article on:. Taking Motrin while breastfeeding. Taking Advil while breastfeeding. Taking Ibuprofen while breastfeeding. Taking Tylenol while breastfeeding. Detailed guideline of breast milk colors Nov 15, Adult breastfeeding: a how-to May 29, Is Chinese Medicine safe while
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